DiTaD (FAQ)
Q: What is DiTaD?
A: DiTaD is an Integrative Network Pharmacology Database Combined with Chemoinformatics and Bioinformatics Tools.
Q: How is DiTaD different from other databases ?
A: There are four unique characteristics which make DiTaD different from any other databases: (1)MIA: More than 3,000 connections manually curated to map ICD (International Classification of Diseases) Disease Codes with ATC (Anatomical Therapeutic Chemical ) Drug Codes. (2)HerbNetPharm: the first network pharmacology of Traditional Chinese Medicines, containing a complete disease- Traditional Chinese Medicines collection (more than 1,500 connections) manually curated from the “Pharmacopoeia of People's Republic of China”.(3)VDDI and VTTD: the first network pharmacology visualization severs of drug-drug interactions and disease-target-drug interactions. (4)Based on the network pharmacology interaction data, the first genome-scale target-drug interaction server (PreDPI-Ki) is developed in DiTaD..
Q: Funcations provided by DiTaD?
A: DiTaD are composed of four functional modules.(1) MIA: Mapping ICD (International Classification of Diseases) Disease Codes with ATC (Anatomical Therapeutic Chemical ) Drug Codes.
(2) HerbNetPharm: Network Pharmacology of Traditional Chinese Medicines.
(3) VNP (VTTD and VDDI): Visual Network Pharmacology.
(4) PreDPI_ki: Genome-Scale Screening of Drug-Target Associations Relevant to Ki Using a Chemogenomics Approach.
Q: Resources for DiTaD?
A: Most DiTaD Records are manually curated by DiTaD team from Original Publications and WHO references. Links are provided for PDB, OMIM, TTD, DrugBank and PubChem.