Drug-Drug Interaction Networks:

• Drug-Drug Interaction: Trastuzumab interacts with Abatacept
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01281
• Interacting Drug Name: Abatacept
• Drug : DB01281 Abatacept ['CTLA4-Ig', 'CTLA4-IgG4m', 'CTLA4Ig', 'CTLA4IgG4m', 'RG-1046', 'RG-2077', 'RG1046', 'RG2077']



---

• Drug-Drug Interaction: Trastuzumab interacts with Abciximab
• Drug-Drug Interaction Description: Abciximab may increase the risk of a hypersensitivy reaction to Trastuzumab.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00054
• Interacting Drug Name: Abciximab
• Drug : DB00054 Abciximab ['7E3 antibody', 'antiGPIIBIIIa', 'c7E3', 'ReoPro']



---

• Drug-Drug Interaction: Trastuzumab interacts with Adalimumab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00051
• Interacting Drug Name: Adalimumab
• Drug : DB00051 Adalimumab ['Ig gamma-1 chain C region']



---

• Drug-Drug Interaction: Trastuzumab interacts with Alemtuzumab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00087
• Interacting Drug Name: Alemtuzumab
• Drug : DB00087 Alemtuzumab []



---

• Drug-Drug Interaction: Trastuzumab interacts with Altretamine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00488
• Interacting Drug Name: Altretamine
• Drug : DB00488 Altretamine Altretamine ['Altretaminum [INN-Latin]', 'HEXAMETHYLMELAMINE', 'HMM', 'HTM', 'HXM']



---

• Drug-Drug Interaction: Trastuzumab interacts with Amsacrine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00276
• Interacting Drug Name: Amsacrine
• Drug : DB00276 Amsacrine Amsacrine ['Acridinyl Anisidide', 'M-AMSA', 'MAMSA']



---

• Drug-Drug Interaction: Trastuzumab interacts with Anakinra
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00026
• Interacting Drug Name: Anakinra
• Drug : DB00026 Anakinra ['ICIL-1RA', 'IL-1ra', 'IL-1RN', 'IL1 inhibitor', 'Interleukin-1 receptor antagonist protein precursor', 'IRAP']



---

• Drug-Drug Interaction: Trastuzumab interacts with Asparaginase
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00023
• Interacting Drug Name: Asparaginase
• Drug : DB00023 Asparaginase ['L-asparagine amidohydrolase', 'Putative L-asparaginase precursor']



---

• Drug-Drug Interaction: Trastuzumab interacts with Azacitidine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00928
• Interacting Drug Name: Azacitidine
• Drug : DB00928 Azacitidine Azacitidine ['5 AZC', 'Azacitidina [INN-Spanish]', 'Azacitidinum [INN-Latin]', 'Azacytidine']



---

• Drug-Drug Interaction: Trastuzumab interacts with Azathioprine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00993
• Interacting Drug Name: Azathioprine
• Drug : DB00993 Azathioprine Azathioprine ['Azathioprin', 'Azathioprine Sodium', 'Azatioprin', 'Azothioprine']



---

• Drug-Drug Interaction: Trastuzumab interacts with Basiliximab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00074
• Interacting Drug Name: Basiliximab
• Drug : DB00074 Basiliximab ['chimeric mouse-human antiCD25', 'Ig gamma-1 chain C region']



---

• Drug-Drug Interaction: Trastuzumab interacts with Betamethasone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00443
• Interacting Drug Name: Betamethasone
• Drug : DB00443 Betamethasone Betamethasone []



---

• Drug-Drug Interaction: Trastuzumab interacts with Bleomycin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00290
• Interacting Drug Name: Bleomycin
• Drug : DB00290 Bleomycin Bleomycin ['Bleocin', 'Bleomicin', 'Bleomicina [INN-Spanish]', 'Bleomycin A2', 'Bleomycin sulfate', 'Bleomycine [INN-French]', 'Bleomycinum [INN-Latin]', 'BLM']



---

• Drug-Drug Interaction: Trastuzumab interacts with Busulfan
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01008
• Interacting Drug Name: Busulfan
• Drug : DB01008 Busulfan Busulfan ['Busulphan', 'Busulphane', 'Butanedioldimethanesulfonate', 'Buzulfan', 'Sulfabutin', 'Sulphabutin', 'Tetramethylene Dimethane Sulfonate', 'Tetramethylenester Kyseliny Methansulfonove']



---

• Drug-Drug Interaction: Trastuzumab interacts with Capecitabine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01101
• Interacting Drug Name: Capecitabine
• Drug : DB01101 Capecitabine Capecitabine ['R340']



---

• Drug-Drug Interaction: Trastuzumab interacts with Carboplatin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00958
• Interacting Drug Name: Carboplatin
• Drug : DB00958 Carboplatin Carboplatin ['CBDCA', 'cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)']



---

• Drug-Drug Interaction: Trastuzumab interacts with Carmustine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00262
• Interacting Drug Name: Carmustine
• Drug : DB00262 Carmustine Carmustine ['BCNU', 'Bischlorethylnitrosourea', 'Bischlorethylnitrosurea', 'Carmustin']



---

• Drug-Drug Interaction: Trastuzumab interacts with Certolizumab Pegol
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB05401
• Interacting Drug Name: Certolizumab Pegol
• Drug : DB05401 Certolizumab Pegol ['CDP870 ']



---

• Drug-Drug Interaction: Trastuzumab interacts with Chlorambucil
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00291
• Interacting Drug Name: Chlorambucil
• Drug : DB00291 Chlorambucil Chlorambucil ['Chlocambucil', 'Chloraminophen', 'Chloraminophene', 'Chlorbutin', 'Chlorbutine', 'Chloroambucil', 'Chlorobutin', 'Chlorobutine', 'Phenylbutyric Acid Nitrogen Mustard']



---

• Drug-Drug Interaction: Trastuzumab interacts with Cisplatin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00515
• Interacting Drug Name: Cisplatin
• Drug : DB00515 Cisplatin Cisplatin ['Cis-DDP', 'Cis-Diamminedichloroplatinum', 'Platinum Ammine Chloride', 'Trans-DDP']



---

• Drug-Drug Interaction: Trastuzumab interacts with Cladribine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00242
• Interacting Drug Name: Cladribine
• Drug : DB00242 Cladribine Cladribine ['2-CdA', "2-Chloro-2'-deoxy-beta-adenosine", "2-Chloro-2'-deoxyadenosine", '2-Chlorodeoxyadenosine', 'Chlorodeoxyadenosine']



---

• Drug-Drug Interaction: Trastuzumab interacts with Clofarabine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00631
• Interacting Drug Name: Clofarabine
• Drug : DB00631 Clofarabine Clofarabine []



---

• Drug-Drug Interaction: Trastuzumab interacts with Corticotropin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01285
• Interacting Drug Name: Corticotropin
• Drug : DB01285 Corticotropin ['ACTH', 'Adrenocorticotopin', 'Adrenocorticotropic hormone', 'Corticotrophin', 'Cortrophin']



---

• Drug-Drug Interaction: Trastuzumab interacts with Cortisone acetate
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01380
• Interacting Drug Name: Cortisone acetate
• Drug : DB01380 Cortisone acetate Cortisone acetate []



---

• Drug-Drug Interaction: Trastuzumab interacts with Cyclophosphamide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00531
• Interacting Drug Name: Cyclophosphamide
• Drug : DB00531 Cyclophosphamide Cyclophosphamide []



---

• Drug-Drug Interaction: Trastuzumab interacts with Cyclosporine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00091
• Interacting Drug Name: Cyclosporine
• Drug : DB00091 Cyclosporine ['Ciclosporin', 'Cyclosporin', 'Cyclosporin A']



---

• Drug-Drug Interaction: Trastuzumab interacts with Cytarabine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00987
• Interacting Drug Name: Cytarabine
• Drug : DB00987 Cytarabine Cytarabine ['Ara-C', 'Arabinocytidine', 'Arabinofuranosylcytosine', 'Arabinosylcytosine', 'AraC', 'Aracytidine', 'Aracytin', 'Aracytine', 'beta-Arabinosylcytosine', 'Beta-cytosine arabinoside', 'beta-D-Arabinosylcytosine', 'Citarabina [INN-Spanish]', 'Cytarabin', 'Cytarabina', 'cytarabine liposome injection', 'Cytarabinoside', 'Cytarabinum [INN-Latin]', 'Cytosine 1-beta-D-arabinofuranoside', 'Cytosine arabinofuranoside', 'Cytosine arabinose', 'Cytosine arabinoside', 'Cytosine beta-D-arabinoside', 'Cytosine-1-beta-D-arabinofuranoside', 'Cytosine-beta-arabinoside', 'Cytosine-beta-D-arabinofuranoside', 'Cytosine, beta-D-arabinoside']



---

• Drug-Drug Interaction: Trastuzumab interacts with Dacarbazine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00851
• Interacting Drug Name: Dacarbazine
• Drug : DB00851 Dacarbazine Dacarbazine ['Biocarbazine R', 'Dacarbazino [INN-Spanish]', 'Dacarbazinum [INN-Latin]', 'DTIC', 'Dtic-Dome', 'DTIE', 'ICDMT', 'ICDT', 'Imidazole Carboxamide']



---

• Drug-Drug Interaction: Trastuzumab interacts with Daclizumab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00111
• Interacting Drug Name: Daclizumab
• Drug : DB00111 Daclizumab ['Anti-IL-2', 'Humanized antiCD25', 'Ig gamma-1 chain C region']



---

• Drug-Drug Interaction: Trastuzumab interacts with Dactinomycin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00970
• Interacting Drug Name: Dactinomycin
• Drug : DB00970 Dactinomycin Dactinomycin ['ActD', 'Actinomycin C1', 'Actinomycin D', 'Dactinomicina [INN-Spanish]', 'Dactinomycine [INN-French]', 'Dactinomycinum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Daunorubicin
• Drug-Drug Interaction Description: Trastuzumab may increase the cardiotoxicity of Daunorubicin. Signs and symptoms of cardiac dysfunction should be monitored for frequently. Increased risk of heart failure. Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00694
• Interacting Drug Name: Daunorubicin
• Drug : DB00694 Daunorubicin Daunorubicin []



---

• Drug-Drug Interaction: Trastuzumab interacts with Denileukin diftitox
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00004
• Interacting Drug Name: Denileukin diftitox
• Drug : DB00004 Denileukin diftitox ['Diphtheria toxin precursor', 'DT', 'NAD(+--diphthamide ADP- ribosyltransferase)']



---

• Drug-Drug Interaction: Trastuzumab interacts with Dexamethasone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01234
• Interacting Drug Name: Dexamethasone
• Drug : DB01234 Dexamethasone Dexamethasone ['Desametasone', 'Desametasone [DCIT]', 'Desamethasone', 'Dexametasona [INN-Spanish]', 'Dexamethasone Acetate', 'Dexamethasone Sodium Phosphate', 'Dexamethasonum [INN-Latin]', 'Dexamethazone', 'Fluormethylprednisolone']



---

• Drug-Drug Interaction: Trastuzumab interacts with Docetaxel
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01248
• Interacting Drug Name: Docetaxel
• Drug : DB01248 Docetaxel Docetaxel ['Docetaxel anhydrous', 'Docetaxel, Trihydrate', 'TXL']



---

• Drug-Drug Interaction: Trastuzumab interacts with Doxorubicin
• Drug-Drug Interaction Description: Trastuzumab may increase the cardiotoxicity of Doxorubicin. Signs and symptoms of cardiac dysfunction should be monitored for frequently. Increased risk of heart failure. Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00997
• Interacting Drug Name: Doxorubicin
• Drug : DB00997 Doxorubicin Doxorubicin ['Doxorubicin HCl', 'Doxorubicin Hydrochloride', 'Doxorubicina [INN-Spanish]', 'Doxorubicine [INN-French]', 'Doxorubicinum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Efalizumab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00095
• Interacting Drug Name: Efalizumab
• Drug : DB00095 Efalizumab ['anti alphaL integrin', 'antiCD11 alpha', 'hu1124', 'Raptiva']



---

• Drug-Drug Interaction: Trastuzumab interacts with Epirubicin
• Drug-Drug Interaction Description: Trastuzumab may increase the cardiotoxicity of Epirubicin. Signs and symptoms of cardiac dysfunction should be monitored for frequently. Increased risk of heart failure. Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00445
• Interacting Drug Name: Epirubicin
• Drug : DB00445 Epirubicin Epirubicin []



---

• Drug-Drug Interaction: Trastuzumab interacts with Erlotinib
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00530
• Interacting Drug Name: Erlotinib
• Drug : DB00530 Erlotinib Erlotinib ['OSI-774']



---

• Drug-Drug Interaction: Trastuzumab interacts with Estramustine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01196
• Interacting Drug Name: Estramustine
• Drug : DB01196 Estramustine Estramustine ['Estramustin Sodium Phosphate', 'Estramustina [INN-Spanish]', 'Estramustine Sodium Phosphate', 'Estramustinum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Etanercept
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00005
• Interacting Drug Name: Etanercept
• Drug : DB00005 Etanercept ['CD120b', 'p75', 'p80 TNF-alpha receptor', 'TNF-R2', 'Tumor necrosis factor receptor 2', 'Tumor necrosis factor receptor superfamily member 1B precursor', 'Tumor necrosis factor receptor type II']



---

• Drug-Drug Interaction: Trastuzumab interacts with Etoposide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00773
• Interacting Drug Name: Etoposide
• Drug : DB00773 Etoposide Etoposide ['(-)-Etoposide', 'Etoposidum [INN-Latin]', 'trans-Etoposide']



---

• Drug-Drug Interaction: Trastuzumab interacts with Floxuridine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00322
• Interacting Drug Name: Floxuridine
• Drug : DB00322 Floxuridine Floxuridine ['5 Fluorodeoxyuridine', '5FDU', 'Deoxyfluorouridine', 'FDUR', 'FDURD', 'Floxiridina [INN-Spanish]', 'Floxuridin', 'Floxuridinum [INN-Latin]', 'Fluorodeoxyuridine', 'Fluoruridine Deoxyribose']



---

• Drug-Drug Interaction: Trastuzumab interacts with Fludarabine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01073
• Interacting Drug Name: Fludarabine
• Drug : DB01073 Fludarabine Fludarabine ['FAMP', "Fludarabine 5'-monophosphate", 'Fludarabine monophosphate', 'Fludarabine phosphate']



---

• Drug-Drug Interaction: Trastuzumab interacts with Fludrocortisone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00687
• Interacting Drug Name: Fludrocortisone
• Drug : DB00687 Fludrocortisone Fludrocortisone []



---

• Drug-Drug Interaction: Trastuzumab interacts with Fluorouracil
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00544
• Interacting Drug Name: Fluorouracil
• Drug : DB00544 Fluorouracil Fluorouracil []



---

• Drug-Drug Interaction: Trastuzumab interacts with Gefitinib
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00317
• Interacting Drug Name: Gefitinib
• Drug : DB00317 Gefitinib Gefitinib []



---

• Drug-Drug Interaction: Trastuzumab interacts with Gemcitabine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00441
• Interacting Drug Name: Gemcitabine
• Drug : DB00441 Gemcitabine Gemcitabine []



---

• Drug-Drug Interaction: Trastuzumab interacts with Hydrocortisone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00741
• Interacting Drug Name: Hydrocortisone
• Drug : DB00741 Hydrocortisone Hydrocortisone ['11beta-Hydroxycortisone', '17alpha-Hydroxycorticosterone', 'Anti-inflammatory hormone', 'Dihydrocostisone', 'Hidrocortisona [INN-Spanish]', 'Hydrocorticosterone', 'Hydrocortisone Acetate', 'Hydrocortisone alcohol', 'Hydrocortisone Base', 'Hydrocortisone Butyrate', 'Hydrocortisone free alcohol', 'Hydrocortisone Sodium Phosphate', 'Hydrocortisone Valerate', 'Hydrocortisonum [INN-Latin]', 'Hydroxycortisone', 'Idrocortisone [DCIT]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Hydroxyurea
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01005
• Interacting Drug Name: Hydroxyurea
• Drug : DB01005 Hydroxyurea Hydroxyurea ['Carbamohydroxamic Acid', 'Carbamohydroximic Acid', 'Carbamohydroxyamic Acid', 'Carbamoyl Oxime', 'Carbamyl Hydroxamate', 'HU', 'Hydroxicarbamidum', 'Hydroxycarbamide', 'Hydroxycarbamine', 'Hydroxylurea', 'Idrossicarbamide [Dcit]', 'N-Carbamoylhydroxylamine', 'N-Hydroxyurea']



---

• Drug-Drug Interaction: Trastuzumab interacts with Ibritumomab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00078
• Interacting Drug Name: Ibritumomab
• Drug : DB00078 Ibritumomab ['Ig gamma-2A chain C region, membrane-bound form', 'radiolabeled murine anti-CD20']



---

• Drug-Drug Interaction: Trastuzumab interacts with Idarubicin
• Drug-Drug Interaction Description: Trastuzumab may increase the cardiotoxicity of Idarubicin. Signs and symptoms of cardiac dysfunction should be monitored for frequently. Increased risk of heart failure. Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01177
• Interacting Drug Name: Idarubicin
• Drug : DB01177 Idarubicin Idarubicin ['Idarubicin Hcl', 'Idarubicin Hydrochloride', 'Idarubicina [INN-Spanish]', 'Idarubicine [INN-French]', 'Idarubicinum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Ifosfamide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01181
• Interacting Drug Name: Ifosfamide
• Drug : DB01181 Ifosfamide Ifosfamide ['Asta Z 4942', 'I-Phosphamide', 'Ifosfamid', 'Ifosfamide Sterile', 'Ifosphamide', 'Ifsofamide', 'Iphosphamid', 'Iphosphamide', 'Isofosfamide', 'Isophosphamide']



---

• Drug-Drug Interaction: Trastuzumab interacts with Imatinib
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00619
• Interacting Drug Name: Imatinib
• Drug : DB00619 Imatinib Imatinib ['Imatinib Mesylate', 'Imatinib Methansulfonate', 'STI-571']



---

• Drug-Drug Interaction: Trastuzumab interacts with Infliximab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00065
• Interacting Drug Name: Infliximab
• Drug : DB00065 Infliximab ['Ig gamma-1 chain C region']



---

• Drug-Drug Interaction: Trastuzumab interacts with Irinotecan
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00762
• Interacting Drug Name: Irinotecan
• Drug : DB00762 Irinotecan Irinotecan ['Irinotecan Hcl', 'Irinotecan Hydrochloride', 'Irinotecan Hydrochloride Trihydrate', 'Irinotecanum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Lenalidomide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00480
• Interacting Drug Name: Lenalidomide
• Drug : DB00480 Lenalidomide Lenalidomide ['CC-5013', 'CDC 501', 'IMiD3']



---

• Drug-Drug Interaction: Trastuzumab interacts with Lomustine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01206
• Interacting Drug Name: Lomustine
• Drug : DB01206 Lomustine Lomustine ['CCNU', 'Chloroethylcyclohexylnitrosourea', 'Lomustina [INN-Spanish]', 'Lomustinum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Mechlorethamine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00888
• Interacting Drug Name: Mechlorethamine
• Drug : DB00888 Mechlorethamine Mechlorethamine ['Chlorethazine', 'Chlormethine', 'HN2', 'MBA', 'Mechloroethamine', 'Mecloretamina', 'Mustine', 'Nitrogen mustard']



---

• Drug-Drug Interaction: Trastuzumab interacts with Melphalan
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01042
• Interacting Drug Name: Melphalan
• Drug : DB01042 Melphalan Melphalan []



---

• Drug-Drug Interaction: Trastuzumab interacts with Mercaptopurine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01033
• Interacting Drug Name: Mercaptopurine
• Drug : DB01033 Mercaptopurine Mercaptopurine ['6 MP', '6-Mercaptopurine', 'Mercaptopurine Monohydrate', 'Mercapurin', 'MP']



---

• Drug-Drug Interaction: Trastuzumab interacts with Methotrexate
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00563
• Interacting Drug Name: Methotrexate
• Drug : DB00563 Methotrexate Methotrexate ['Amethopterin', 'Amethopterine', 'HDMTX', 'L-Amethopterin', 'Methopterin', 'Methotextrate', 'Methotrexat', 'Methotrexate Sodium', 'Methylaminopterin', 'Methylaminopterinum', 'MTX', 'N-Bismethylpteroylglutamic Acid']



---

• Drug-Drug Interaction: Trastuzumab interacts with Methylprednisolone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00959
• Interacting Drug Name: Methylprednisolone
• Drug : DB00959 Methylprednisolone Methylprednisolone ['6alpha-Methylprednisolone', 'Methyleneprednisolone', 'Methylprednisolon', 'Methylprednisolonum [INN-Latin]', 'Metilprednisolona [INN-Spanish]', 'Metilprednisolone [Dcit]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Mitomycin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00305
• Interacting Drug Name: Mitomycin
• Drug : DB00305 Mitomycin Mitomycin ['7-Amino-9α-methoxymitosane', 'Mitamycin', 'MMC']



---

• Drug-Drug Interaction: Trastuzumab interacts with Mitoxantrone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01204
• Interacting Drug Name: Mitoxantrone
• Drug : DB01204 Mitoxantrone Mitoxantrone ['Mitoxanthrone', 'Mitoxantron']



---

• Drug-Drug Interaction: Trastuzumab interacts with Muromonab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00075
• Interacting Drug Name: Muromonab
• Drug : DB00075 Muromonab ['AntiCD3', 'Muromonab-CD3']



---

• Drug-Drug Interaction: Trastuzumab interacts with Mycophenolate mofetil
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00688
• Interacting Drug Name: Mycophenolate mofetil
• Drug : DB00688 Mycophenolate mofetil Mycophenolate mofetil ['Mycophenylate mofetil']



---

• Drug-Drug Interaction: Trastuzumab interacts with Mycophenolic acid
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01024
• Interacting Drug Name: Mycophenolic acid
• Drug : DB01024 Mycophenolic acid Mycophenolic acid ['Mycophenoic acid']



---

• Drug-Drug Interaction: Trastuzumab interacts with Natalizumab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00108
• Interacting Drug Name: Natalizumab
• Drug : DB00108 Natalizumab ['Anti-alpha4 integrin', 'Anti-VLA4']



---

• Drug-Drug Interaction: Trastuzumab interacts with Nelarabine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01280
• Interacting Drug Name: Nelarabine
• Drug : DB01280 Nelarabine Nelarabine ['GW-506U78', 'Nelzarabine']



---

• Drug-Drug Interaction: Trastuzumab interacts with Nilotinib
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB04868
• Interacting Drug Name: Nilotinib
• Drug : DB04868 Nilotinib Nilotinib ['AMN-107', 'AMN107']



---

• Drug-Drug Interaction: Trastuzumab interacts with Oxaliplatin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00526
• Interacting Drug Name: Oxaliplatin
• Drug : DB00526 Oxaliplatin Oxaliplatin ['Oxaliplatin [Usan:Inn:Ban]', 'Oxaliplatino [Spanish]', 'Oxaliplatinum [Latin]', 'Oxaloplatine [French]', 'Oxaloplatino [Spanish]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Paclitaxel
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Concomitant therapy may also increase Trastuzumab serum concentration and decrease Paclitaxel serum concentrations. Monitor closely for adverse events and therapeutic response.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01229
• Interacting Drug Name: Paclitaxel
• Drug : DB01229 Paclitaxel Paclitaxel ['7-epi-Paclitaxel', '7-epi-Taxol', '7-Epipaclitaxel', '7-Epitaxol', 'ABI-007']



---

• Drug-Drug Interaction: Trastuzumab interacts with Pegaspargase
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00059
• Interacting Drug Name: Pegaspargase
• Drug : DB00059 Pegaspargase ['L-asparagine amidohydrolase', 'Putative L-asparaginase precursor']



---

• Drug-Drug Interaction: Trastuzumab interacts with Pentostatin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00552
• Interacting Drug Name: Pentostatin
• Drug : DB00552 Pentostatin Pentostatin ["2'-DCF", "2'-Deoxycoformycin", "2'-Dexoycoformycin", 'Deoxycoformycin']



---

• Drug-Drug Interaction: Trastuzumab interacts with Prednisolone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00860
• Interacting Drug Name: Prednisolone
• Drug : DB00860 Prednisolone Prednisolone ['Deltahydrocortisone', 'Methylprednisolone Acetate', 'PRDL', 'Predisolone Sodium Phosphate', 'Prednisolona [INN-Spanish]', 'Prednisolone Acetate', 'Prednisolone Sodium Phosphate', 'Prednisolone Tebutate', 'Prednisolonum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Prednisone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00635
• Interacting Drug Name: Prednisone
• Drug : DB00635 Prednisone Prednisone ['Dehydrocortisone', 'Prednisona [INN-Spanish]', 'Prednisonum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Procarbazine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01168
• Interacting Drug Name: Procarbazine
• Drug : DB01168 Procarbazine Procarbazine ['Ibenzmethyzin', 'Ibenzmethyzine', 'Ibenzmethyzine hydrochloride', 'IBZ', 'MBH', 'MIH', 'MIH Hydrochloride', 'PCB hydrochloride', 'PCX', 'Procarbazin', 'Procarbazin [German]', 'Procarbazina [INN-Spanish]', 'Procarbazine hydrochloride', 'Procarbazinum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Rilonacept
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB06372
• Interacting Drug Name: Rilonacept
• Drug : DB06372 Rilonacept ['Arcalyst', 'interleukin-1 (IL-1) trap']



---

• Drug-Drug Interaction: Trastuzumab interacts with Rituximab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00073
• Interacting Drug Name: Rituximab
• Drug : DB00073 Rituximab ['AntiCD20', 'Ig gamma-1 chain C region']



---

• Drug-Drug Interaction: Trastuzumab interacts with Sirolimus
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00877
• Interacting Drug Name: Sirolimus
• Drug : DB00877 Sirolimus Sirolimus ['(-)-Rapamycin', 'Rapamycin']



---

• Drug-Drug Interaction: Trastuzumab interacts with Sorafenib
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00398
• Interacting Drug Name: Sorafenib
• Drug : DB00398 Sorafenib Sorafenib ['Sorafenib tosylate']



---

• Drug-Drug Interaction: Trastuzumab interacts with Streptozocin
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00428
• Interacting Drug Name: Streptozocin
• Drug : DB00428 Streptozocin Streptozocin []



---

• Drug-Drug Interaction: Trastuzumab interacts with Sunitinib
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01268
• Interacting Drug Name: Sunitinib
• Drug : DB01268 Sunitinib Sunitinib ['SU11248', 'Sunitinib malate', 'Sutent']



---

• Drug-Drug Interaction: Trastuzumab interacts with Tacrolimus
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00864
• Interacting Drug Name: Tacrolimus
• Drug : DB00864 Tacrolimus Tacrolimus ['FK-506', 'FK5', 'K506', 'Tacarolimus', 'tacrolimus hydrate']



---

• Drug-Drug Interaction: Trastuzumab interacts with Temozolomide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00853
• Interacting Drug Name: Temozolomide
• Drug : DB00853 Temozolomide Temozolomide ['Methazolastone', 'Temozolamide', 'Temozolodida [Spanish]', 'Temozolomidum [Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Temsirolimus
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB06287
• Interacting Drug Name: Temsirolimus
• Drug : DB06287 Temsirolimus Temsirolimus ['CCI-779']



---

• Drug-Drug Interaction: Trastuzumab interacts with Teniposide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00444
• Interacting Drug Name: Teniposide
• Drug : DB00444 Teniposide Teniposide ['Teniposido [INN-Spanish]', 'Teniposidum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Thalidomide
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01041
• Interacting Drug Name: Thalidomide
• Drug : DB01041 Thalidomide Thalidomide ['alpha-phthalimidoglutarimide', 'N-Phthalimidoglutamic acid imide', 'N-Phthaloylglutamimide', 'N-Phthalylglutamic acid imide', 'Thalidomine USP26']



---

• Drug-Drug Interaction: Trastuzumab interacts with Thioguanine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00352
• Interacting Drug Name: Thioguanine
• Drug : DB00352 Thioguanine Thioguanine ['2-Amino 6MP', '2-Amino-6-mercaptopurine', '2-Amino-6-merkaptopurin', '2-Amino-6-purinethiol', '2-Aminopurin-6-thiol', '2-Aminopurine-6-thiol', '2-Aminopurine-6(1H)-thione', '6-Mercapto-2-aminopurine', '6-Mercaptoguanine', '6-Thioguanine', 'TG', 'ThG', 'Tioguanin', 'Tioguanine']



---

• Drug-Drug Interaction: Trastuzumab interacts with Thiotepa
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB04572
• Interacting Drug Name: Thiotepa
• Drug : DB04572 Thiotepa Thiotepa []



---

• Drug-Drug Interaction: Trastuzumab interacts with Topotecan
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB01030
• Interacting Drug Name: Topotecan
• Drug : DB01030 Topotecan Topotecan ['Topotecan Hcl', 'Topotecan Hydrochloride', 'Topotecan Lactone', 'Topotecane [INN-French]', 'Topotecanum [INN-Latin]']



---

• Drug-Drug Interaction: Trastuzumab interacts with Tositumomab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00081
• Interacting Drug Name: Tositumomab
• Drug : DB00081 Tositumomab ['Ig gamma-1 chain C region']



---

• Drug-Drug Interaction: Trastuzumab interacts with Tretinoin
• Drug-Drug Interaction Description: Increased risk of leukopenia and anemia due to synergistic effects. Monitor for signs and symptoms of adverse events during concomitant therapy.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00755
• Interacting Drug Name: Tretinoin
• Drug : DB00755 Tretinoin Tretinoin ['All Trans Retinoic Acid', 'All Trans-Retinoic Acid', 'ATRA', 'beta-Retinoic Acid', 'Retionic Acid']



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• Drug-Drug Interaction: Trastuzumab interacts with Triamcinolone
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00620
• Interacting Drug Name: Triamcinolone
• Drug : DB00620 Triamcinolone Triamcinolone ['Fluoxiprednisolone', 'Fluoxyprednisolone', 'Tiamcinolonum [INN-Latin]', 'Triamcinalone', 'Triamcinolona [INN-Spanish]', 'Triamcinolone acetonide', 'Triamcinolone diacetate', 'Triamcinolone hexacetonide', 'Triamcinolonum [INN]']



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• Drug-Drug Interaction: Trastuzumab interacts with Valrubicin
• Drug-Drug Interaction Description: Trastuzumab may increase the cardiotoxicity of Valrubicin. Signs and symptoms of cardiac dysfunction should be monitored for frequently. Increased risk of heart failure. Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00385
• Interacting Drug Name: Valrubicin
• Drug : DB00385 Valrubicin Valrubicin ['Antibiotic Ad 32']



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• Drug-Drug Interaction: Trastuzumab interacts with Vinblastine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00570
• Interacting Drug Name: Vinblastine
• Drug : DB00570 Vinblastine Vinblastine []



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• Drug-Drug Interaction: Trastuzumab interacts with Vincristine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00541
• Interacting Drug Name: Vincristine
• Drug : DB00541 Vincristine Vincristine ['22-Oxovincaleukoblastine', 'Indole alkaloid', 'LCR', 'Leurocristine', 'VCR', 'VIN', 'Vincristina [DCIT]', 'Vincristine Sulfate', 'Vincristinum [INN-Latin]', 'Vincrstine', 'Vincrystine', 'Z-D-Val-Lys(Z)-OH']



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• Drug-Drug Interaction: Trastuzumab interacts with Vinorelbine
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00072
• Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



• Second Drug ID: DB00361
• Interacting Drug Name: Vinorelbine
• Drug : DB00361 Vinorelbine Vinorelbine ['Vinorelbin', 'Vinorelbina [Spanish]', 'Vinorelbine Bitartrate', 'Vinorelbine Ditartarate', 'Vinorelbine Ditartrate', 'Vinorelbine Tartrate', 'Vinorelbinum [Latin]']



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