Drug-Drug Interaction Networks:

• Drug-Drug Interaction: Tositumomab interacts with Natalizumab
• Drug-Drug Interaction Description: The immunosuppressant, Tositumomab, may increase the adverse effects of Natalizumab. Increased risk of Progressive Multifocal Leukoencephalopathy (PML) and other infections. Concurrent therapy should be avoided.
• First Drug ID: DB00081
• Drug Name: Tositumomab
• Drug : DB00081 Tositumomab ['Ig gamma-1 chain C region']



• Second Drug ID: DB00108
• Interacting Drug Name: Natalizumab
• Drug : DB00108 Natalizumab ['Anti-alpha4 integrin', 'Anti-VLA4']



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• Drug-Drug Interaction: Tositumomab interacts with Trastuzumab
• Drug-Drug Interaction Description: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
• First Drug ID: DB00081
• Drug Name: Tositumomab
• Drug : DB00081 Tositumomab ['Ig gamma-1 chain C region']



• Second Drug ID: DB00072
• Interacting Drug Name: Trastuzumab
• Drug : DB00072 Trastuzumab ['Anti HER2', 'Ig gamma-1 chain C region']



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