Reaction List:

• Reaction Equation: ATP + protein >> ADP + a phosphoprotein



• EC Numbers and Enzyme Link: 2.7.11.1
• KEGG Reaction ID: R00162
• MetaCyc Reaction ID: 2.7.11.11-RXN,2.7.11.12-RXN,2.7.11.13-RXN,2.7.11.17-RXN,2.7.11.21-RXN,2.7.11.22-RXN,2.7.11.24-RXN,2.7.12.1-RXN,2.7.12.2-RXN,PROTEIN-KINASE-RXN
• BRENDA Reaction ID: 44300,323335,353176
• KEGG Commentary: general reaction
• MetaCyc Commentary: cAMP is required to activate this enzyme. The inactive holoenzyme of cAMP-dependent protein kinase is a tetramer composed of two regulatory (R) and two catalytic (C) subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP molecules and two free monomeric catalytic subunits (i.e. R(2)C(2) + 4 cAMP = R(2)(cAMP)(4) + 2 C).EMBER-SORT-FN - NUMBERED-CLASS-SORT-FNFFICIAL-EC? - TYNYNONYMS - PKA CYNONYMS - protein kinase AYNONYMS - STK22YSTEMATIC-NAME - ATP:protein phosphotransferase (cAMP-dependent)